Dr. Michael Haglund will speak on the development of a comprehensive neurosurgery effort in Africa that focuses on the 4Ts: Twinning, Training, Technology, and the Top-Down Approach. His effort over the last 12 years in collaboration with the Duke Global Health Institute and the Department of Neurosurgery has led to the launching of the first in the nation Division of Global Neurosurgery and Neurology. The Division which had its foundation with 2 DGHI graduate students was founded in 2014 and now counts over 75 members including faculty, fellows, neurosurgery residents, graduate students, and staff both at Duke and in Uganda. The group has published over 50 manuscripts on global health in the last three years. Dr. Haglund will describe how the 4Ts has been vital to the success of the global neurosurgery division both at home and in Uganda.
Dr. Michael Haglund’s areas of subspecialty in neurosurgery include the surgical treatment of epilepsy and functional mapping for resection of brain tumors. The major areas of research include the cortical organization of higher cognitive functions as well as the mechanisms and pathways underlying the propagation of seizure activity. Research into the cortical organization of higher cognitive functions includes language organization, memory and face processing involving electrical stimulation mapping in patients undergoing awake craniotomies and the use of optical imaging to localize areas of the neocortex serving specific cognitive processes. The mechanisms underlying the pathways and propagation of seizures involves using two models. The in vivo model, primate visual cortex, provides access to understanding the functional organization of the primate visual cortex and how seizure activity spreads through these known pathways. The pathways are investigated using microelectrode recordings as well as optical imaging. The second model, an in vitro slice preparation, involves using both rat and human neocortical slices. Propagation of seizure activity through normal pathways is studied using intracellular and extracellular electrode recording which is combined with optical imaging of the normal activity and abnormal seizure activity propagation. By better understanding how the normal cortex in humans is organized and how abnormal activity such as seizures is propagated, improvements in the surgical treatment of epilepsy will be accomplished. Other areas of interests include the use of dynamic optical imaging to study the grading and localization of intrinsic brain tumors. As one of the authors on two U.S. patents which involve this technique, the ability to study brain tumors and other tumors not involving the brain using optical imaging may improve our ability to obtain more complete resections and to noninvasively screen and monitor many types of tumors.
This presentation is sponsored by the John Hope Franklin Center and Africa Initiative. A light lunch will be served. Parking is available in nearby Trent Rd. and Erwin Rd. parking decks. The series provides 1-hour parking vouchers to guests.